Co-staining human PBMCs with fluorescent antibodies and antibody-oligonucleotide conjugates for cell sorting prior to single-cell CITE-Seq

Summary: The dual interrogation of the transcriptome and proteome with single-cell resolution provides exquisite insights into immune mechanisms in health and disease.Here, we describe a cutting-edge protocol wherein we combine Cellular precis vodka Indexing of Transcriptomes and Epitopes by Sequencing (CITE-Seq), a technique utilizing antibody-oli

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Effectiveness of methenamine hippurate in preventing urinary tract infections: an updated systematic review, meta-analysis and trial sequential analysis of randomized controlled trials

Abstract Introduction Urinary Tract Infections (UTIs) are a significant health problem worldwide, especially among women.methenamine hippurate has been proposed as a preventive measure against recurrent UTIs.This updated systematic review and meta-analysis aimed to evaluate the effectiveness of methenamine hippurate in preventing UTIs, incorporatin

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Midgut Mitochondrial Function as a Gatekeeper for Malaria Parasite Infection and Development in the Mosquito Host

Across diverse organisms, various physiologies are profoundly regulated abc material by mitochondrial function, which is defined by mitochondrial fusion, biogenesis, oxidative phosphorylation (OXPHOS), and mitophagy.Based on our data and significant published studies from Caenorhabditis elegans, Drosophila melanogaster and mammals, we propose that

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