Summary: The dual interrogation of the transcriptome and proteome with single-cell resolution provides exquisite insights into immune mechanisms in health and disease.Here, we describe a cutting-edge protocol wherein we combine Cellular precis vodka Indexing of Transcriptomes and Epitopes by Sequencing (CITE-Seq), a technique utilizing antibody-oli
Effectiveness of methenamine hippurate in preventing urinary tract infections: an updated systematic review, meta-analysis and trial sequential analysis of randomized controlled trials
Abstract Introduction Urinary Tract Infections (UTIs) are a significant health problem worldwide, especially among women.methenamine hippurate has been proposed as a preventive measure against recurrent UTIs.This updated systematic review and meta-analysis aimed to evaluate the effectiveness of methenamine hippurate in preventing UTIs, incorporatin
Urinary K+ promotes irritative voiding symptoms and pain in the face of urothelial barrier dysfunction
Abstract The internal surface of the bladder is lined by the urothelium, a stratified epithelium that forms an impermeable barrier to water and urine constituents.Abnormalities in the urothelial barrier have been described in certain forms of cystitis and were hypothesized to contribute to irritative voiding symptoms and pain by allowing the permea
The incidence of Pyrenochaeta terrestris in root of different plant species in Serbia
Root samples of cereals opi chill em with kindness (oats, wheat, barley, maize and sorghum), vegetables (garlic, onion, pepper, cucumber, pumpkin, carrot and tomato), industrial plant (soya bean) and weeds (Johnson grass, barnyard grass and green bristle-grass) collected in different agroecological conditions in Serbia were analysed for the presenc
Midgut Mitochondrial Function as a Gatekeeper for Malaria Parasite Infection and Development in the Mosquito Host
Across diverse organisms, various physiologies are profoundly regulated abc material by mitochondrial function, which is defined by mitochondrial fusion, biogenesis, oxidative phosphorylation (OXPHOS), and mitophagy.Based on our data and significant published studies from Caenorhabditis elegans, Drosophila melanogaster and mammals, we propose that